Ongoing Project
Outer Membrane Vesicles and Cancer
Outer Membrane Vesicles and Cancer
Outer membrane vesicles are spherical lipid vesicles that result from budding of the outer membrane of various bacteria. We are working on defining the relationship between bacterial outer membrane vesicles and the biology of colonic epithelia and cancer stem cells.
Collaborators
Dr. Leigh Greathouse (Baylor, Dept. of Nutritional Science), webpage
Link between OMVs and Cancer
Microbiota shed vesicles containing number biomolecules. These molecules have the potential to modulate the biology of the host epithelium or immune system, potentially affecting homeostasis and cancer progression.
