Previous Pinney Group Members
Former Postdoctoral Research Associates
Dr. Rajeswari
Mukherjee
Education:
M.S. Organic Chemistry (2005) and B.S. Chemistry (2003): University of Calcutta, Kolkata, West Bengal, India; Ph.D.Organic Chemistry (2015): Wake Forest University,Winston-Salem, NC, USA; Current project: Scale-up of Lead Cathepsin L Inhibitors
Dr. Deboprosad Mondal
Jiangli Song, Ph.D.
Education: B.S. Chemistry and Biochemistry, August 2012
Ph.D. Organic Chemistry, Baylor University (2012)
Dissertation entitled: “Design and Synthesis of Non-peptidic Thiosemicarbazone Derivatives as Inhibitors of Cathepsins L and K.” Postdoctoral Associate, Baylor University (2007-2013)
Dr. Rajendra Tanpure
Education: B.S. Chemistry, R.Y.K. Science College, Nasik, India;
M.S. Organic Chemistry, IIT Mumbai, India;
Ph.D. Organic Chemistry, Baylor University (2003)
Postdoctoral Fellowship, Scripps Research Institute, La Jolla (2004-2005);
Postdoctoral Fellowship, UCLA (2005-2007);
Postdoctoral Fellowship, Baylor University (2007-2012)
Dr. Kishore Kumar Gaddale Devanna
Education: B.S., M.S. Chemistry, Vivekananda College, Madras University, Chennai, India;
Ph.D. Synthetic Organic Chemistry, Indian Institute of Technology Madras (IITM), Chennai, India.
Postdoctoral Associate, UTMB, Galveston, TX (2005-2007);
Postdoctoral Associate, Baylor University (2007-2010)
Dr. Madhavi Sriram
Dr. Rajsekhar Guddneppanavar
Teacher-Scholar Postdoctoral Fellow, Department of Chemsitry, Wake Forest University
Dr. Ming Zhou
Dr. Vani Mocharla
Dr. Anjan Ghatak
Dr. Nandeo Choony
Former Graduate Students
Graham Carlson
Education:
B.S. Chemistry, Hope College, Holland, MI, 2014;
Ph.D. in Chemistry, 2021
Jacob Ford
Education: B.S. Chemistry, University of Texas – Tyler, TX, 2013;
Ph.D. Chemistry, 2021
Casey Maguire
Education:
B.S. Biochemistry, St. Edward’s University, 2012
Ph.D. Chemistry, 2019
Haichan Niu
Ph.D. (Chemistry and Biochemistry), December 15, 2018
Dissertation entitled: “Efficient Synthetic Methodology for the Construction of Dihydronaphthalene and Benzosuberene Molecular Scaffolds and Structure Guided Design, Synthesis and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization”
Lauren Freeman
Education:
B.S. Chemistry, Baylor University, 2015
Graduated December 2021
Zhe Shi
Ph.D. (Chemistry and Biochemistry), August 11, 2018
Dissertation entitled: “Small-Molecule Inhibitors of Tubulin Polymerization as Vascular Disrupting Agents and Prodrugs Targeting Tumor-Associated Hypoxia”
Blake Winn
Ph.D. (Chemistry and Biochemistry), May 2017
Dissertation entitled: “Synthesis, Characterization, and Biological Evaluation of Bioreductively Activatable Prodrug Conjugates (BAPCs) of Phenstatin, KGP18, OXi6196, Combretastatin A-1, and Combretastatin A-4”
Christine Herdman
Ph.D. (Chemistry and Biochemistry), August, 2016
Dissertation entitled: “Synthesis and Biological Evaluation of Potential Vascular Disrupting and Antimitotic Agents Utilizing Benzosuberene, Benzocyclooctene, and Indene Molecular Frameworks”
Erica Parker
Education:
B.S. Chemistry, Texas A&M University-Commerce, 2009
Graduated December 2015
Chen-Ming “Eric” Lin
Education:
B.S. Pharmaceutical Science, National Taiwan University, Taipei, Taiwan, 2005
Graduated December 2015
Laxman Devkota
Education:
M.S. Organic Chemistry, Tribhuvan University, Kathmandu, Nepal, 2005
Experience: Lecturer in Chemistry, Kathmandu University, Nepal, 2006-2009
Graduated December 2015
Matt MacDonough, Ph.D.
Chemistry and Biochemistry, December 2013.
Dissertation entitled: “The Design, Synthesis, and Biological Evaluation of Indole-based Anticancer Agents.”
Jiangli Song, Ph.D.
Chemistry and Biochemistry, August 2012
Dissertation entitled: “Design and Synthesis of Non-peptidic Thiosemicarbazone Derivatives as Inhibitors of Cathepsins L and K.”
Clinton George, Ph.D.
Chemistry and Biochemistry, May 2012
Dissertation entitled: “Targeting the Tumor Microenvironment through the Design and Synthesis of Highly Cytotoxic Anticancer Agents.”
Lindsay Jones, Ph.D.
Chemistry and Biochemistry, May 2012
Dissertation entitled: “Design and Synthesis of Functionalized Small-Molecule Inhibitors of Cathepsins L and K.”
Benson Nguyen, Ph.D.
Chemistry and Biochemistry, December, 2010
Dissertation entitled: “Design and Synthesis of Combretastatin A-1 Analogs, Small Molecule Vascular Disrupting Agents, and Bioreductive Triggers as Potential Therapeutic Agents for the Treatment of Cancer.”
Gerardo Arturo Elguezabal-Torralba, Ph.D.
Chemistry and Biochemistry, August, 2010
Dissertation entitled: “Design and Synthesis of Potential Serotonin-Selective Reuptake Inhibitors and Serotonin-Norepinephrine Reuptake Inhibitors for the Treatment of Depression.”
John J. Hall, Ph.D. (Chemistry and Biochemistry), May, 2008 (co-mentored by Dr. Mary Lynn Trawick)
Dissertation entitled: “Inhibitors of Tubulin, Nitric Oxide Synthase, and HIF-1 Alpha; Synthesis, Biological, and Biochemical Evaluation.”
Madhavi Sriram, Ph.D., December, 2007
Dissertation entitled: “Design, Synthesis, Biochemical, and Biological Evaluation of Benzocyclic and Enediyne Analogs of Combretastatins as Potential Tubulin Binding Ligands in the Treatment of Cancer.”
J. Freeland Ackley, M.S., December 2007
Thesis entitled: “Design, Synthesis and Evaluation of Di-nitrogen Derivatives of Combretastatin and Novel Cruzain Inhibiting Compounds for the Treatment of Chagas Disease”
Abhishek Dogra, M.S., December 2006
Thesis entitled: “Design and Synthesis of Dihydronaphthalene Vascular Disrupting Agents and Indolequinone-Based Bioreductives.”
M. Graciela Miranda, Ph.D., August, 2006
Dissertation entitled: “Design, Synthesis and Biological Evaluation of Novel Serotonin Reuptake Inhibitors and Novel Derivatives of a Nitrogen-Containing Combretastatin Analog.”
Rogelio Siles, Ph.D., December, 2005
Dissertation entitled: “Design, Synthesis and Biological Evaluation of New Anti-Cancer Nitrogen-Containing Combretastatins and Novel Cysteine Protease Inhibitors for the Treatment of Chagas Disease.”
Phyllis Arthasery, Ph.D., December, 2005
Dissertation entitled: “Discovery and Development of Unique Small Molecule Chromene Based Ligands and Combretastatin Analogs as Potential Second Generation Vascular Disrupting Agents Towards Cancer Chemotherapy.”
Hani Wehbe, Ph.D. (Institute of Biomedical Studies), August 2005(co-mentored by Dr. Christopher Kearney)
Dissertation entitled: “Towards Enhanced Cancer Chemotherapy: Studies on Drug Design, Synergy, and Drug Target Expression and Resistance with the Combretastatins and Other Chemotherapeutics.”
Mallinath B. Hadimani, Ph.D., December 2004
Dissertation entitled: “Studies Toward the Discovery of New Classes of Privileged Molecules as Colchicine-Site Binding Ligands for Tubulin: Structure-Based Design, Synthesis, and Bioactivity of Small Ligands Targeted at Tumor Vasculature.”
Christopher J. Jelinek, M.S., December 2004
Thesis entitled: “Discovery and Development of Dihydronaphthalene-Based Vascular Targeting Agents and Combretastatin-Related Analogs.”
Rajendra Prakash Tanpure, Ph.D., December, 2003
Dissertation entitled: “New Synthetic Methodology for the Stereoselective Preparation of Functionalized Conjugated Dienes from Alkynyl Oxirane Precursors: Synthesis and Biological Evaluation of Functionalized Triarylalkenes as Tubulin Binding Agents.”
Raymond J. Kessler, M.S., December, 2002
Thesis entitled: “Synthesis and Evaluation of New Inhibitors of Tubulin Polymerization and Their Corresponding Prodrugs as Potential Vascular Targeting Agents.”
Anupama Ramesh Shirali, Ph.D., August, 2002
Dissertation entitled: “Inhibitors of Tubulin Assembly: Designed Ligands Featuring Benzo[b]thiophene, Dihydronaphthalene and Aroylchromene Molecular Core Structures.”
David A. Walsh, M.S., August, 2002
Thesis entitled: “Synthesis and Evaluation of Conjugated One-Ynes (COYs) as a Novel Class of Anti-Cancer Drugs and ?-Turn Peptidomimetics as Viable Substitutes for the Alkene Bridge in Combretastatin A-4.”
James M. Dorsey, M.S., December, 2001
Thesis entitled: “Synthesis of Serotonin-Selective Reuptake Inhibitors With Novel Side Chains: Designing a Serotonin Reuptake Inhibitor with an Improved Adverse Reaction Profile.”
Heather O’Dell, M.A. (Biology, non-thesis), August, 2001
Successfully defended the oral research presentation portion of her MA degree in Biology on June 21, 2001 through a talk entitled: “The Biological Evaluation of Potential Vascular Targeting Agents.” Heather carried out a portion of her research in Dr. Kevin G. Pinney’s laboratory and then completed a six month internship in Professor Klaus Edvardsen’s laboratory in Lund, Sweden working in the area of tumor immunology.
Zhi Chen, M.S., December, 2000
Thesis entitled: “Synthesis of Tubulin Binding Ligands Incorporating Dihydronaphthalene, Indene, and Benzo[b]thiophene Molecular Frameworks and Preparation of Their Corresponding Phosphorous Containing Prodrugs as Tumor Specific Vascular Targeting Agents.”
Vani P. Mocharla, Ph.D., December, 1999
Dissertation entitled: “Design, Synthesis, and Biological Evaluation of Diverse Small Molecular Frameworks As Tubulin Binding Ligands.”
Maria del Pilar Mejia, Ph.D., May, 1999
Dissertation entitled: “Synthesis and Biological Evaluation of Novel Photoaffinity Labeling Reagents and Nitrogen Containing Compounds Modeled After Combretastatin A-4.”
Feng Wang, M.S., May, 1999
Thesis entitled: “Stereoselective Synthesis of Conjugated Diene Systems and Design of New Tubulin Polymerization Inhibitors as Antimitotic Agents.”
Amanda Crippen-Harkrider, M.S. December, 1998
Thesis entitled: “Designed Inhibitors of Tubulin Polymerization: Tamoxifen-Based Analogs.” (name listed as Amanda R. Harkrider on actual thesis).
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