— Baylor University (@Baylor) February 13, 2019
The Taube Lab is excited to start another semester and another year! We are one grad student and a few undergrads stronger, and have lots of exciting research on the horizon. To keep progress consistent, we are resolving to implement better time management techniques and efficient work flow. One way we talked about doing this is via the Eisenhower Box. Our goal? Aim for tasks to be in the Not Urgent/Important category. Below is the version we created:
The Taube Lab is very excited to warmly welcome our newest addition: Shuxuan Song! She rotated with us at the beginning of the semester and left a wonderful impression. She is a first year PhD student coming to us from China, and has a rich history in medicine. We are sure she will bring in many great ideas and much creativity.
SABCS (San Antonio Breast Cancer Symposium) was a valuable experience, getting the chance to interact with clinicians, translational researchers, and basic scientists. Keighley and Kelsey both presented on the third day of the nearly-week-long conference, but at different times so they could still see each other’s posters. Kelsey is pictured flexing her great mentoring skills with an undergrad from a different lab who was the conference. Keighley got creative with mixed media for her poster presentation, shown here with her iPad, which let viewers see her images much clearer. Both grad students were busy throughout their sessions– always a good sign! Congrats to both!
The Taube Lab (Dr. Taube, Kelsey, and Keighley) have all made it safely to the San Antonio Breast Cancer Symposium. It’s an amazing, huge, international conference where scientists and physicians from all angles of breast cancer meet to learn from and discuss with each other. Day 1 has been an interesting day, hearing talks about EMT, brain metastasis, TNBC clinical care, BRCA1/2, dormancy, and more!
Keighley has been live tweeting some of the speakers; stay up to date by following her Twitter (@knreisenauer) or the conference (@SABCSSanAntonio).
We are excited for the San Antonio Breast Cancer Symposium 12/4-8/2018 where both our doctoral students, Keighley and Kelsey, will be presenting their research. Keighley’s abstract on cancer stem cell sensitization to treatment with small-molecules has been accepted to the ‘tumor cell and molecular biology: new drugs and mechanisms’ theme and Kelsey’s abstract is titled “Defining chromatin accessibility profiles of partial and reversible EMT.”
The Taube Lab is proud to support Susan G. Komen’s Race for the Cure this year, being held in Waco! If you’d like to join our team, or support the cause, follow this link! We are thankful for your support!
Outgrowth of disseminated metastases is the major cause of mortality in cancer patients. In the Taube lab, we are investigating the molecular pathways and cellular properties which enable primary tumor cells to metastasize.
In normal tissues, epithelial cells form a well-structured barrier using a variety of adhesion molecules. However, aberrant activation of a conserved cellular program, termed epithelial-mesenchymal transition (EMT), facilitates the separation of epithelial cells from this tissue. When EMT occurs in epithelial tumors, the probability of metastatic dissemination is increased.
The Taube Lab is focused on uncovering the regulatory mechanisms which facilitate EMT in both normal and cancerous settings, describing the specific targets and roles of these regulatory mechanisms and testing small molecule inhibitors of these proteins to ultimately lead to novel therapeutic strategies.