Vector Biology Lab

Welcome to the Sim Vector Biology Lab at Baylor University.  Our lab focuses on developing novel mosquito control strategies using a combination of genetics, genomics and molecular biology.  Click the link below to learn more about our projects.

Driven by Science, Guided by Compassion

 

Science can be a powerful driver of change—but only when it’s acted upon with empathy. Our genetic technology, genomic data, and genetic manipulation strategies help suffering people and health agencies get the tools they need to prevent infectious diseases from spreading to millions of people.

The Vector Biology Laboratory focuses on developing novel genetic control strategies using a combination of genetics, genomics, and molecular biology. The two broad areas of work in our laboratory are to understand (1) mechanisms of sex determination and transmission ratio distortion in mosquitoes; and (2) diapause biology on the mosquito Culex pipiens, which is the primary vector for West Nile encephalitis, Eastern equine encephalitis, and many other arboviruses, as well as lymphatic filariases.

Successful results are shedding light not only on the mechanisms controlling mosquito development, but also on a variety of ways to control disease vectors including genetic manipulation technology.

You can find the reasons for our research from the fascinating video clips below!

Learn About Specific Projects

THE ROLE OF INSULIN/FOXO PATHWAY IN CULEX PIPIENS DIAPAUSE

The objective of this proposal is to understand the molecular mechanisms of diapause in adults of the northern house mosquito, Culex pipiens, the vector of West Nile virus, with the long-term goal of disrupting the mosquito’s biological processes during this vulnerable phase of the life cycle.

MECHANISMS OF SEX DETERMINATION AND SEX RATIO DISTORTION IN CULEX PIPIENS

This objective of this project is to understand how regulatory genes control sex determination in male and female Culex pipiens mosquitoes.

MEET OUR TEAM

At Baylor University, the Sim Lab consists of both undergraduate and graduate students working on a variety of projects.  Click below to learn more about the people behind the research in our lab.

Get in Touch!

Click the button below to contact us if you have any questions.